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Mutational Analysis of the Mycobacteriophage BPs Promoter P(R) Reveals Context-Dependent Sequences for Mycobacterial Gene Expression

The P(R) promoter of mycobacteriophage BPs directs early lytic gene expression and is under the control of the BPs repressor, gp33. Reporter gene fusions showed that P(R) has modest activity in an extrachromosomal context but has activity that is barely detectable in an integrated context, even in t...

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Autori principali: Oldfield, Lauren M., Hatfull, Graham F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187689/
https://ncbi.nlm.nih.gov/pubmed/25092027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01801-14
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