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Microbial Peptidyl-Prolyl cis/trans Isomerases (PPIases): Virulence Factors and Potential Alternative Drug Targets

SUMMARY: Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases (PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at peptidyl bonds preceding proline residues. Intense searches revealed that PPIases are a superfamily of...

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Bibliografiset tiedot
Päätekijät: Ünal, Can M., Steinert, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187684/
https://ncbi.nlm.nih.gov/pubmed/25184565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00015-14
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