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The obesity‐associated gene Negr1 regulates aspects of energy balance in rat hypothalamic areas

Neural growth regulator 1 (Negr1) is among the first common variants that have been associated with the regulation of body mass index. Using AAV technology directed to manipulate Negr1 expression in vivo, we find that decreased expression of Negr1 in periventricular hypothalamic areas leads to incre...

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Autors principals: Boender, Arjen J., van Gestel, Margriet A., Garner, Keith M., Luijendijk, Mieneke C. M., Adan, Roger A. H.
Format: Artigo
Idioma:Inglês
Publicat: Wiley Periodicals, Inc. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187548/
https://ncbi.nlm.nih.gov/pubmed/25077509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12083
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