CD3 Antibody and IL‐2 Complex Combination Therapy Inhibits Atherosclerosis by Augmenting a Regulatory Immune Response

BACKGROUND: Accumulating evidence suggests that the balance between pathogenic effector T cells (Teffs) and regulatory T cells (Tregs) may be important for controlling atherosclerotic disease. We hypothesized that a combination therapy with anti‐CD3 antibody (CD3‐Ab) and IL‐2/anti‐IL‐2 monoclonal an...

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Hlavní autoři: Kasahara, Kazuyuki, Sasaki, Naoto, Yamashita, Tomoya, Kita, Tomoyuki, Yodoi, Keiko, Sasaki, Yoshihiro, Takeda, Masafumi, Hirata, Ken‐ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187475/
https://ncbi.nlm.nih.gov/pubmed/24755152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000719
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