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Comparison of Cortical and White Matter Traumatic Brain Injury Models Reveals Differential Effects in the Subventricular Zone and Divergent Sonic Hedgehog Signaling Pathways in Neuroblasts and Oligodendrocyte Progenitors

The regenerative capacity of the central nervous system must be optimized to promote repair following traumatic brain injury (TBI) and may differ with the site and form of damage. Sonic hedgehog (Shh) maintains neural stem cells and promotes oligodendrogenesis. We examined whether Shh signaling cont...

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Detalhes bibliográficos
Main Authors: Mierzwa, Amanda J., Sullivan, Genevieve M., Beer, Laurel A., Ahn, Sohyun, Armstrong, Regina C.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187014/
https://ncbi.nlm.nih.gov/pubmed/25290062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091414551782
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