Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats

AIM: To investigate the metabolite changes caused by simvastatin or fenofibrate intervention in diet-induced hyperlipidemia rats using a GC-MS-based metabolomic profiling approach. METHODS: SD rats were fed with high-lipid diet for 4 weeks to induce hyperlipidemia, then the rats were fed with normal...

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Main Authors: Xu, Qiu-yu, Liu, Yin-hui, Zhang, Qi, Ma, Bo, Yang, Zhen-dong, Liu, Lei, Yao, Di, Cui, Guang-bo, Sun, Jing-jing, Wu, Zi-mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186989/
https://ncbi.nlm.nih.gov/pubmed/25220639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.72
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