Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice

AIM: To investigate whether alpha-lipoic acid (ALA) could attenuate the insulin resistance and metabolic disorders in high fat diet-fed mice. METHODS: Male mice were fed a high fat diet (HFD) plus ALA (100 and 200 mg·kg(−1)·d(−1)) or HFD plus a positive control drug metformin (300 mg·kg(−1)·d(−1)) f...

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Detalhes bibliográficos
Main Authors: Yang, Yi, Li, Wang, Liu, Yang, Li, Yan, Gao, Ling, Zhao, Jia-jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186984/
https://ncbi.nlm.nih.gov/pubmed/25152027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.64
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