Epistasis between SPINK5 and TSLP Genes Contributes to Childhood Asthma

BACKGROUND: Epithelial genes have previously been associated with asthma, but only explain a small fraction of heritability. In part, this may be due to epistasis that is often not considered. OBJECTIVE: To determine independent and epistatic associations between FLG, SPINK5 and TSLP gene variants a...

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Main Authors: Biagini Myers, Jocelyn M., Martin, Lisa J., Butsch Kovacic, Melinda, Mersha, Tesfaye B., He, Hua, Pilipenko, Valentina, Lindsey, Mark A., Ericksen, Mark B., Bernstein, David I, LeMasters, Grace K., Lockey, James E., Khurana Hershey, Gurjit K.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186896/
https://ncbi.nlm.nih.gov/pubmed/24831437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.03.037
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