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Short Hairpin RNA Library-Based Functional Screening Identified Ribosomal Protein L31 That Modulates Prostate Cancer Cell Growth via p53 Pathway

Androgen receptor is a primary transcription factor involved in the proliferation of prostate cancer cells. Thus, hormone therapy using antiandrogens, such as bicalutamide, is a first-line treatment for the disease. Although hormone therapy initially reduces the tumor burden, many patients eventuall...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maruyama, Yojiro, Miyazaki, Toshiaki, Ikeda, Kazuhiro, Okumura, Toshiyuki, Sato, Wataru, Horie-Inoue, Kuniko, Okamoto, Koji, Takeda, Satoru, Inoue, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186824/
https://ncbi.nlm.nih.gov/pubmed/25285958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108743
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