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An International Interpretation Study Using the ALK IHC Antibody D5F3 and a Sensitive Detection Kit Demonstrates High Concordance between ALK IHC and ALK FISH and between Evaluators

INTRODUCTION: The goal of personalized medicine is to treat patients with a therapy predicted to be efficacious based on the molecular characteristics of the tumor, thereby sparing the patient futile or toxic therapy. Anaplastic lymphoma kinase (ALK) inhibitors are effective against ALK-positive non...

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Main Authors: Wynes, Murry W., Sholl, Lynette M., Dietel, Manfred, Schuuring, Ed, Tsao, Ming S., Yatabe, Yasushi, Tubbs, Raymond R., Hirsch, Fred R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186652/
https://ncbi.nlm.nih.gov/pubmed/24722153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000115
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