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Regulation of insulin-like growth factor signaling by metformin in endometrial cancer cells
Obesity, diabetes and insulin resistance are marked risk factors that promote the development of type I endometrial cancer. Previous studies have demonstrated that insulin-like growth factor 1 (IGF-1) and IGF-2 promote cell proliferation in endometrial cancer cells, while metformin reverses this eff...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
D.A. Spandidos
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186557/ https://ncbi.nlm.nih.gov/pubmed/25289085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2466 |
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