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Transcriptional Complexity in Autosomal Recessive Polycystic Kidney Disease
BACKGROUND AND OBJECTIVES: Autosomal recessive polycystic kidney disease (ARPKD) is caused by mutations in the PKHD1 gene. The longest open reading frame comprises 66 exons encoding polyductin or fibrocystin, a type I transmembrane protein with 4074 amino acids. Functional investigations are conside...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186505/ https://ncbi.nlm.nih.gov/pubmed/25104275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.00920114 |
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