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Adaptive Resistance to Immunotherapy Directed Against p53 Can be Overcome by Global Expression of Tumor-Antigens in Dendritic Cells

Immunotherapy of cancer utilizes dendritic cells (DCs) for antigen presentation and the induction of tumor-specific immune responses. However, the therapeutic induction of anti-tumor immunity is limited by tumor escape mechanisms. In this study, immortalized dendritic D2SC/1 cells were transduced wi...

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Autors principals: Humar, Matjaz, Azemar, Marc, Maurer, Martina, Groner, Bernd
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186483/
https://ncbi.nlm.nih.gov/pubmed/25340039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00270
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