Prosaposin regulates coenzyme Q10 levels in HepG2 cells, especially those in mitochondria

Coenzyme Q10 (CoQ10) is a key component of the mitochondrial electron transfer chain and is one of the most important cellular antioxidants. We previously reported that glycoprotein saposin B (SapB) binds CoQ10 in human cells. To elucidate the physiological role of SapB and its precursor, prosaposin...

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Главные авторы: Kashiba, Misato, Oizumi, Mikiko, Suzuki, Masaru, Sawamura, Yoshimi, Nagashima, Kohei, Yoshimura, Shinichi, Yamamoto, Yorihiro
Формат: Artigo
Язык:Inglês
Опубликовано: the Society for Free Radical Research Japan 2014
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186375/
https://ncbi.nlm.nih.gov/pubmed/25320454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.13-106
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