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Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/loxP and tetracycline-off systems

In the present study, the tetracycline-off and Cre/loxP systems were combined to gain temporal and spatial control of transgene expression. Mice were generated that carried three transgenes: Tie2-tTA, tet-O-Cre and either the ZEG or ZAP reporter. Tie2-tTA directs expression of tetracycline-controlle...

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Bibliografske podrobnosti
Main Authors: LIU, JU, DEUTSCH, URBAN, FUNG, IRIS, LOBE, CORRINNE G.
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186360/
https://ncbi.nlm.nih.gov/pubmed/25289022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1965
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