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Enhancer RNA facilitates NELF release from immediate early genes
Enhancer RNAs (eRNAs) are a class of long noncoding RNAs (lncRNA) expressed from active enhancers, whose function and action mechanism are yet to be firmly established. Here we show that eRNAs facilitate the transition of paused RNA Polymerase II (RNAPII) into productive elongation by acting as a de...
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Glavni autori: | , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186258/ https://ncbi.nlm.nih.gov/pubmed/25263592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.08.023 |
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