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P01.04 THERAPEUTIC POTENTIAL OF TARGETING HOX PROTEIN FUNCTION IN GLIOBLASTOMA

BACKGROUND: Resistance of glioblastoma to standard chemoradiotherapy may be mediated, at least partially, by a population of inherently resistant glioma stem cells (GSCs) which are able to survive treatment and reconstitute the tumour. HOX genes are dysregulated in various cancers and a subset of GS...

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Bibliografiske detaljer
Main Authors: Brend, T., Kelly, Z., Ajaz, M., Morgan, R., Pandha, H., Short, S.C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185869/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.97
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