P01.03 FUNCTIONAL CHARACTERISATION OF THE ISOCITRATE DEHYDROGENASE 1 (IDH 1) R132H MUTATION IN GLIOMAS

INTRODUCTION: Diffuse gliomas are the most prevalent brain tumors in adults and cannot be cured. Amino-acid substitution at position 132 of cytoplasmic enzyme isocitrate dehydrogenase 1 (IDH1) are characteristic for lower grade gliomas and therefrom derived secondary glioblastomas (GBM). The most fr...

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Bibliografiska uppgifter
Huvudupphovsmän: Biedermann, J., El-Ardat, K.Abou, Conde, M., Wiedemuth, R., Peitzsch, M., Eisenhofer, G., Kunz-Schughart, L., Temme, A., Schröck, E., Klink, B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Poster Presentations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185868/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.96
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