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O10.10 RESULTS OF NIMOTUZUMAB AND VINORELBINE, RADIATION AND RE-IRRADIATION FOR DIFFUSE PONTINE GLIOMA IN CHILDHOOD

BACKGROUND: Radiotherapy is the only treatment definitely indicated for diffuse pontine gliomas (DIPG). Data on the role of EGFR signaling in the onset of childhood DIPG prompted the use of an anti-EGFR monoclonal antibody, nimotuzumab. Based on a possible synergistic activity with vinorelbine and r...

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Bibliografiske detaljer
Main Authors: Massimino, M., Biassoni, V., Miceli, R., Schiavello, E., Warmuth-Metz, M., Modena, P., Giangaspero, F., Spreafico, F., Bach, F., Gandola, L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185863/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.91
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