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P17.17 INHIBITION OF DNA DAMAGE RESPONSE ABROGATES GLIOBLASTOMA CANCER STEM CELL RADIORESISTANCE

GBM recurrence following radiotherapy is due to a subset of tumour propagating cells with stem like characteristics (cancer stem cells, CSC). CSCs have the ability to recapitulate the tumour of origin whereas the majority of tumour cells (tumour bulk) do not. CSCs in GBM have been reported to exhibi...

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Bibliografiske detaljer
Main Authors: Carruthers, R., Ahmed, S., Chalmers, A.J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185713/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.347
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