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P17.15 AUTOCRINE SPHINGOSINE-1-PHOSPHATE FUELS GROWTH AND STEMNESS IN GLIOBLASTOMA STEM CELLS

Sphingosine-1-phosphate (S1P) is an onco-promoter lipid that, after interaction with specific membrane receptors, acts as a key regulator of growth, invasion, and therapy-resistance of different tumors, including human glioblastomas (GBMs). These are the most common and lethal primary brain cancer i...

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Autors principals: Di Vito, C., Navone, S., Abdel Hadi, L., Giussani, P., Viani, P., Rampini, P.M., Caroli, M., Marfia, G., Campanella, R., Riboni, L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185711/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.345
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