P04.18 PROGNOSIS IMPACT OF THE REGIONAL DISTRIBUTION OF MGMT GENE METHYLATION ACCORDING TO THE CPGISLAND METHYLATOR PHENOTYPE AND AGE IN HIGH-GRADE GLIOMAS

Clinical and molecular prognostic factors in gliomas include age, IDH mutation, the glioma CpG island methylator phenotype (G-CIMP) and promoter methylation of the O6-methylguanine DNA-methyltransferase (MGMT) gene, among others. Clinical trials supported the predictive value of MGMT promoter methyl...

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Detalhes bibliográficos
Main Authors: Mur, P., de Lope, A. Rodriguez, Hernandez-Iglesias, T., Diaz, F., Ribalta, T., Fiaño, C., Garcia, J.F., Rey, J.A., Mollejo, M., Meléndez, B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Poster Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185495/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.150
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