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P04.05 HISTONE MUTATIONS IN CHILDHOOD AND YOUNG ADULT HIGH GRADE GLIOMA

BACKGROUND: High grade gliomas in children and young adults are clinically and genetically different from their adult counterparts. Recurrent mutations of the H3F3A gene coding for the H3.3 isoform of the H3 histone have recently been described. These mutations have been shown to be exclusive to hig...

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Autores principales: Bekaert, L., Bazille, C., Borha, A., Vasiljevic, A., Jouvet, A., Lechapt-Zalcman, E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185480/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.137
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