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P01.15 ASSESSMENT OF A NOVEL MODIFIED KYTOZYME NANOPARTICLE TO CROSS AN ‘ALL HUMAN’ BLOOD BRAIN BARRIER MODEL

The blood brain barrier (BBB) consists mainly of endothelial cells, astrocytes and pericytes embedded in a specialized basement membrane. To properly evaluate the ability of novel brain tumour therapeutics to cross the BBB, an ‘all human’ model that better reflects in vivo conditions, critical for t...

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Bibliografiske detaljer
Main Authors: Maherally, Z., Philpott, R., Barbu, E., Fillmore, H.L., Pilkington, G.J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185448/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.108
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