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P01.11 ATF4 AS A MEDIATOR OF RESISTANCE TO TARGETED THERAPY IN HIGH-GRADE GLIOMAS

Small molecule inhibitors have been investigated in a large set of clinical trials in malignant gliomas. Despite promising preclinical studies, results of pilot trials have been generally disappointing. A deeper understanding of the complex biology of malignant glioma cells, and their adaptation to...

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Detalhes bibliográficos
Main Authors: Moeckel, S., Neyns, B., Pan, E., Riemenschneider, M., Bosserhoff, A., Vollmann-Zwerenz, A., Hau, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185444/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.104
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