The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection—suramin inhibits EV71 infection in vitro and in vivo

Enterovirus 71 (EV71) causes severe central nervous system infections, leading to cardiopulmonary complications and death in young children. There is an urgent unmet medical need for new pharmaceutical agents to control EV71 infections. Using a multidisciplinary approach, we found that the approved...

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Autors principals: Ren, Peijun, Zou, Gang, Bailly, Benjamin, Xu, Shanshan, Zeng, Mei, Chen, Xinsheng, Shen, Liang, Zhang, Ying, Guillon, Patrice, Arenzana-Seisdedos, Fernando, Buchy, Philippe, Li, Jian, von Itzstein, Mark, Li, Qihan, Altmeyer, Ralf
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185360/
https://ncbi.nlm.nih.gov/pubmed/26038755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2014.60
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