UV and melanoma: the TP53 link

Ultraviolet radiation (UVR) is a major risk factor for melanoma development, but it has been unclear exactly how UVR leads to melanomagenesis. In a recent publication in Nature, Viros et al. identify TP53/Trp53 as a UVR-target gene in melanoma and show that UVR-induced TP53/Trp53 mutations accelerat...

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Bibliografiske detaljer
Main Authors: Choi, Yeon Sook, Fisher, David E
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Research Highlight
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185355/
https://ncbi.nlm.nih.gov/pubmed/25033756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.95
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