Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity

Mediator complex is a molecular hub integrating signaling, transcription factors, and RNA polymerase II (RNAPII) machinery. Mediator MED23 is involved in adipogenesis and smooth muscle cell differentiation, suggesting its role in energy homeostasis. Here, through the generation and analysis of a liv...

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Main Authors: Chu, Yajing, Rosso, Leonardo Gómez, Huang, Ping, Wang, Zhichao, Xu, Yichi, Yao, Xiao, Bao, Menghan, Yan, Jun, Song, Haiyun, Wang, Gang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185346/
https://ncbi.nlm.nih.gov/pubmed/25223702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.120
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