PSMA-Specific CAR-Engineered T Cells Eradicate Disseminated Prostate Cancer in Preclinical Models

Immunology-based interventions have been proposed as a promising curative chance to effectively attack postoperative minimal residual disease and distant metastatic localizations of prostate tumors. We developed a chimeric antigen receptor (CAR) construct targeting the human prostate-specific membra...

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Detalhes bibliográficos
Main Authors: Zuccolotto, Gaia, Fracasso, Giulio, Merlo, Anna, Montagner, Isabella Monia, Rondina, Maria, Bobisse, Sara, Figini, Mariangela, Cingarlini, Sara, Colombatti, Marco, Zanovello, Paola, Rosato, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184866/
https://ncbi.nlm.nih.gov/pubmed/25279468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109427
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