Critical Role of Exogenous Nitric Oxide in ROCK Activity in Vascular Smooth Muscle Cells

OBJECTIVE: Rho-associated kinase (ROCK) signaling pathway has been shown to mediate various cellular functions including cell proliferation, migration, adhesion, apoptosis, and contraction, all of which may be involved in pathogenesis of atherosclerosis. Endogenous nitric oxide (NO) is well known to...

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Autors principals: Maruhashi, Tatsuya, Noma, Kensuke, Iwamoto, Yumiko, Iwamoto, Akimichi, Oda, Nozomu, Kajikawa, Masato, Matsumoto, Takeshi, Hidaka, Takayuki, Kihara, Yasuki, Chayama, Kazuaki, Nakashima, Ayumu, Goto, Chikara, Liao, James K., Higashi, Yukihito
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184841/
https://ncbi.nlm.nih.gov/pubmed/25280018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109017
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