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Evaluation of Proteomic Search Engines for the Analysis of Histone Modifications

[Image: see text] Identification of histone post-translational modifications (PTMs) is challenging for proteomics search engines. Including many histone PTMs in one search increases the number of candidate peptides dramatically, leading to low search speed and fewer identified spectra. To evaluate d...

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Autori principali: Yuan, Zuo-Fei, Lin, Shu, Molden, Rosalynn C., Garcia, Benjamin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184451/
https://ncbi.nlm.nih.gov/pubmed/25167464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr5008015
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