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Synthesis of Partially O-Acetylated N-Acetylneuraminic Acid Using Regioselective Silyl Exchange Technology

[Image: see text] Postglycosylation acetylation of sialic acid imparts unique roles to sialoglycoconjugates in mammalian immune response making structural and functional understanding of these analogues important. Five partially O-acetylated Neu5Ac analogues have been synthesized. Reaction of per-O-...

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Autori principali: Park, Simon S., Gervay-Hague, Jacquelyn
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184446/
https://ncbi.nlm.nih.gov/pubmed/25247390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502389g
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