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Improving peak detection in high-resolution LC/MS metabolomics data using preexisting knowledge and machine learning approach

Motivation: Peak detection is a key step in the preprocessing of untargeted metabolomics data generated from high-resolution liquid chromatography-mass spectrometry (LC/MS). The common practice is to use filters with predetermined parameters to select peaks in the LC/MS profile. This rigid approach...

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Detalhes bibliográficos
Main Authors: Yu, Tianwei, Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184266/
https://ncbi.nlm.nih.gov/pubmed/25005748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu430
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