The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in systemic lupus erythematosus

PPAR-γ agonists can suppress autoimmune responses and renal inflammation in murine lupus but the mechanisms implicated in this process remain unclear. We tested the effect of the PPAR-γ agonist pioglitazone in human lupus and control PBMCs with regards to gene regulation and various functional assay...

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Bibliografske podrobnosti
Main Authors: Zhao, Wenpu, Berthier, Celine C., Lewis, Emily E., McCune, W. Joseph, Kretzler, Matthias, Kaplan, Mariana J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184099/
https://ncbi.nlm.nih.gov/pubmed/23962407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2013.07.002
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