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STAT3 supports experimental K-RasG12D–induced murine myeloproliferative neoplasms dependent on serine phosphorylation

Juvenile myelomonocytic leukemia, acute myeloid leukemia (AML), and other myeloproliferative neoplasms (MPNs) are genetically heterogeneous but frequently display activating mutations in Ras GTPases and activation of signal transducer and activator of transcription 3 (STAT3). Altered STAT3 activity...

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Detalhes bibliográficos
Main Authors: Gough, Daniel J., Marié, Isabelle J., Lobry, Camille, Aifantis, Iannis, Levy, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183984/
https://ncbi.nlm.nih.gov/pubmed/25150294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-484196
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