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An antibody reactive to the Gly(63)–Lys(68) epitope of NT-proBNP exhibits O-glycosylation-independent binding

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP exhibits heavy O-linked glycosylation, and it is quite difficult to develop an antibod...

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Bibliografske podrobnosti
Main Authors: Lee, Yujean, Kim, Hyori, Chung, Junho
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183943/
https://ncbi.nlm.nih.gov/pubmed/25236766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.57
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