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An antibody reactive to the Gly(63)–Lys(68) epitope of NT-proBNP exhibits O-glycosylation-independent binding
The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP exhibits heavy O-linked glycosylation, and it is quite difficult to develop an antibod...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183943/ https://ncbi.nlm.nih.gov/pubmed/25236766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.57 |
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