Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy

BACKGROUND: Host immunity is emerging as a key player in the prognosis and response to treatment of cancer patients. However, the impact of the immune system and its modulation by therapies are unknown in rare soft tissue sarcomas such as solitary fibrous tumours (SFTs), whose management in the adva...

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Autors principals: Tazzari, M, Negri, T, Rini, F, Vergani, B, Huber, V, Villa, A, Dagrada, P, Colombo, C, Fiore, M, Gronchi, A, Stacchiotti, S, Casali, P G, Pilotti, S, Rivoltini, L, Castelli, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183857/
https://ncbi.nlm.nih.gov/pubmed/25101565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.437
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