Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway

BACKGROUND: Insulin-like growth factor binding protein-2 (IGFBP-2) is significantly increased in the serum of patients with malignant gliomas. High plasma IGFBP-2 levels are correlated with poor prognosis in glioma patients. However, the exact role of exogenous IGFBP-2 in gliomas is unclear. METHODS...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Han, S, Li, Z, Master, L M, Master, Z W, Wu, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183856/
https://ncbi.nlm.nih.gov/pubmed/25093489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.435
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker