BRCA1 mRNA levels following a 4–6-week intervention with oral 3,3′-diindolylmethane

BACKGROUND: Haploinsufficiency may contribute to the development of breast cancer among women with a BRCA1 mutation. Thus, interventions that enhance BRCA1 expression may represent avenues for prevention. Studies have shown that 3,3′-diindolylmethane (DIM) can upregulate BRCA1 expression in breast c...

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Autors principals: Kotsopoulos, J, Zhang, S, Akbari, M, Salmena, L, Llacuachaqui, M, Zeligs, M, Sun, P, Narod, S A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Clinical Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183839/
https://ncbi.nlm.nih.gov/pubmed/25025957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.391
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