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The Toxoplasma Pseudokinase ROP5 Is an Allosteric Inhibitor of the Immunity-related GTPases

The Red Queen hypothesis proposes that there is an evolutionary arms race between host and pathogen. One possible example of such a phenomenon could be the recently discovered interaction between host defense proteins known as immunity-related GTPases (IRGs) and a family of rhoptry pseudokinases (RO...

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Detalhes bibliográficos
Main Authors: Reese, Michael L., Shah, Niket, Boothroyd, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183819/
https://ncbi.nlm.nih.gov/pubmed/25118287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567057
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