HIV Acquisition Is Associated with Increased Antimicrobial Peptides and Reduced HIV Neutralizing IgA in the Foreskin Prepuce of Uncircumcised Men

BACKGROUND: The foreskin is the site of most HIV acquisition in uncircumcised heterosexual men. Although HIV-exposed, seronegative (HESN) uncircumcised men demonstrate HIV-neutralizing IgA and increased antimicrobial peptides (AMPs) in the foreskin prepuce, no prospective studies have examined the m...

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Detalhes bibliográficos
Main Authors: Hirbod, Taha, Kong, Xiangrong, Kigozi, Godgrey, Ndyanabo, Anthony, Serwadda, David, Prodger, Jessica L., Tobian, Aaron A., Nalugoda, Fred, Wawer, Maria J., Shahabi, Kamnoosh, Rojas, Olga L., Gommerman, Jennifer L., Broliden, Kristina, Kaul, Rupert, Gray, Ronald H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183701/
https://ncbi.nlm.nih.gov/pubmed/25275513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004416
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