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A Fibril-Like Assembly of Oligomers of a Peptide Derived from β-Amyloid

[Image: see text] A macrocyclic β-sheet peptide containing two nonapeptide segments based on Aβ(15–23) (QKLVFFAED) forms fibril-like assemblies of oligomers in the solid state. The X-ray crystallographic structure of macrocyclic β-sheet peptide 3 was determined at 1.75 Å resolution. The macrocycle f...

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Detalhes bibliográficos
Main Authors: Pham, Johnny D., Spencer, Ryan K., Chen, Kevin H., Nowick, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183627/
https://ncbi.nlm.nih.gov/pubmed/25068693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja505713y
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