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IL-32γ Delays Spontaneous Apoptosis of Human Neutrophils through MCL-1, Regulated Primarily by the p38 MAPK Pathway

IL-32γ is a multifunctional cytokine involved in various inflammatory and auto-immune diseases in which neutrophils can affect the evolution of these diseases. To persist at inflammatory sites, neutrophils require inhibition of their rapid and constitutive apoptosis, an inhibitory effect that phlogo...

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Détails bibliographiques
Auteurs principaux: Allaeys, Isabelle, Gymninova, Irina, Canet-Jourdan, Charlotte, Poubelle, Patrice E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183585/
https://ncbi.nlm.nih.gov/pubmed/25275312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109256
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