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No effect of weight loss on LINE-1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women

OBJECTIVES: Obesity and weight-loss are associated with methylation patterns in specific genes, but their effect on Long Interspersed Nuclear Elements (LINE-1) methylation, a measure of global methylation is largely unknown. METHODS: Three hundred overweight/obese post-menopausal women (50–75 years)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duggan, Catherine, Xiao, Liren, Terry, Mary Beth, McTiernan, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183146/
https://ncbi.nlm.nih.gov/pubmed/24930817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20806
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