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PALB2: THE HUB OF A NETWORK OF TUMOR SUPPRESSORS INVOLVED IN DNA DAMAGE RESPONSES
PALB2 was first identified as a partner of BRCA2 that mediates its recruitment to sites of DNA damage. PALB2 was subsequently found as a tumor suppressor gene. Inherited heterozygosity for this gene is associated with an increased risk of cancer of the breast and other sites. Additionally, biallelic...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183126/ https://ncbi.nlm.nih.gov/pubmed/24998779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2014.06.003 |
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