Androgen Suppresses the Proliferation of Androgen Receptor-Positive Castration-Resistant Prostate Cancer Cells via Inhibition of Cdk2, CyclinA, and Skp2

The majority of prostate cancer (PCa) patient receiving androgen ablation therapy eventually develop castration-resistant prostate cancer (CRPC). We previously reported that androgen treatment suppresses Skp2 and c-Myc through androgen receptor (AR) and induced G1 cell cycle arrest in androgen-indep...

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Detalhes bibliográficos
Main Authors: Kokontis, John M., Lin, Hui-Ping, Jiang, Shih Sheng, Lin, Ching-Yu, Fukuchi, Junichi, Hiipakka, Richard A., Chung, Chi-Jung, Chan, Tzu-Min, Liao, Shutsung, Chang, Chung-Ho, Chuu, Chih-Pin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182885/
https://ncbi.nlm.nih.gov/pubmed/25271736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109170
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