Disc1 Variation Leads to Specific Alterations in Adult Neurogenesis

Disrupted in schizophrenia 1 (DISC1) is a risk factor for a spectrum of neuropsychiatric illnesses including schizophrenia, bipolar disorder, and major depressive disorder. Here we use two missense Disc1 mouse mutants, described previously with distinct behavioural phenotypes, to demonstrate that Di...

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Autors principals: Chandran, Jayanth S., Kazanis, Ilias, Clapcote, Steven J., Ogawa, Fumiaki, Millar, J. Kirsty, Porteous, David J., ffrench-Constant, Charles
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182707/
https://ncbi.nlm.nih.gov/pubmed/25272038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108088
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