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The Actin-Sequestering Protein Thymosin Beta-4 Is a Novel Target of Hypoxia-Inducible Nitric Oxide and HIF-1α Regulation
The actin-sequestering protein thymosin beta-4 (Tβ4) is involved in various cellular and physiological processes such as proliferation, motility, growth and metastasis. Nitric oxide (NO) promotes tumor invasiveness and metastasis by activating various enzymes. Herein, we investigated whether hypoxia...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182666/ https://ncbi.nlm.nih.gov/pubmed/25271630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106532 |
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