Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

Consistent with recent reports indicating that neurons differentiated in vitro from human-induced pluripotent stem cells (hiPSCs) are immature relative to those in the human brain, gene expression comparisons of our hiPSC-derived neurons to the Allen BrainSpan Atlas indicate that they most resemble...

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Autors principals: Brennand, K, Savas, J N, Kim, Y, Tran, N, Simone, A, Hashimoto-Torii, K, Beaumont, K G, Kim, H J, Topol, A, Ladran, I, Abdelrahim, M, Matikainen-Ankney, B, Chao, S-h, Mrksich, M, Rakic, P, Fang, G, Zhang, B, Yates, J R, Gage, F H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182344/
https://ncbi.nlm.nih.gov/pubmed/24686136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.22
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